Description
Indications
- Chemotherapy-Induced Nausea & Vomiting
- Postoperative Nausea & Vomiting
- Radiation-Induced Nausea & Vomiting
- Cholestatic Pruritus (Off-label)
- Uremic Pruritus (Off-label)
- Spinal Opioid-Induced Pruritus (Off-label)
- Rosacea (Off-label)
- Hyperemesis Gravidarum
Dosage and Administration
- Chemotherapy-Induced Nausea & Vomiting (Prophylaxis)
- ORAL
- Moderately emetogenic chemotherapy: 8 mg started 30 minutes before chemotherapy, then q12hr for 1-2 days after chemotherapy
- Highly emetogenic chemotherapy: 24 mg started 30 minutes before chemotherapy
- IV
- 0.15 mg/kg over 15 min administered 30 min before chemotherapy, then 4 and 8 hr after first dose; not to exceed 16 mg, or as prescribed by the doctor.
- Postoperative Nausea & Vomiting (Prophylaxis)
- 4 mg IV/IM immediately before anesthesia or after procedure or 16 mg orally 1 hr before anesthesia
- Radiation-Induced Nausea & Vomiting (Prophylaxis)
- Total body radiation therapy: 8 mg orally 1-2 hours before radiation therapy; administered each day
- Single high-dose fraction therapy to abdomen: 8 mg orally 1-2 hr before radiation therapy; administer subsequent doses every 8 hr after first dose 1-2 days after completion of therapy
- Daily fractions to abdomen: Administer 8 mg orally 1-2 hr before radiotherapy; administer subsequent doses every 8 hr after first dose each day radiotherapy is given
Contraindications
- Refer to the manufacturer’s labeling for further details.
Common side-effects
- Refer to the manufacturer’s labeling for further information.
Reminder
- A doctor’s prescription is required to purchase this product. To process your order more efficiently and prevent cancellation, please upload it. During delivery, our delivery team will verify your original prescription and keep it ready. Please keep your original SC/PWD ID & booklet ready for validation if you used it during purchase.
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